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The digestion products were separated and purified using a continuous-density gradient of iodixanol, with densities ranging from 1.060 to 1.100 0.01 g/mL

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Importantly, low Se levels in pregnant women affect fetal growth and augment the risk of delivering a small-for-gestational age infant by reducing placental antioxidant defense, while low Se in the third trimester is thought to indicate increased demands by the placenta, an issue which requires further confirmation

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